Tuesday, September 27, 2016

Enalapril and Hydrochlorothiazide

Generic Name : Enalapril and Hydrochlorothiazide

Pronunciation : e nal' a pril - hye droe klor oh thye' a zide

Trade Name(s): 
India- Enace-D Tab, Enam-D Tab, Enapril-Ht Tab, Enapril-Ld Tab, Enaretic Tab , Envas-H Tab , Enzide Tab, Invozide Tab , Normace-D Tab, Vasonorm-H Tab , Viviril-D Tab.
International- Vaseretic.


Why it is prescribed (Indications) : 
This medication is an angiotensin-converting enzyme (ACE) inhibitor and thiazide diuretic combination, prescribed for high blood pressure.





When it is not to be taken (Contraindications): 


Contraindicated in patients with anuria, angioedema and hypersensitivity.







Pregnancy Category :












A B C D X
Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
Adult: PO- HTN; CHF- Per tab contains enalapril maleate 10 mg and hydrochlorothiazide 25 mg: ½-1 tab/day.


How it should be taken : 
It comes as a tablet to take by mouth, with or without food.




Special Instruction : 
* Caution should be exercised in patients with history of heart, parathyroid, liver or kidney disease, lupus, sugar, any allergy, asthma, gout, angioedema, who are taking other medications, elderly, children, during pregnancy and breastfeeding.


* Avoid alcohol consumption.



* It may cause diarrhea or vomiting which leads to dehydration, drink enough fluid to avoid this problem.



* It may cause dizziness, lightheadedness or fainting, do not drive a car or operate machinery while taking this medication.



* Avoid exposure to sunlight; otherwise it may cause sunburn.


Side Effects : 
Most frequent -

Dizziness, headache, fatigue, muscle cramps, weakness, impotence, diarrhea and increased cough.
Body As A Whole -


Fainting, chest pain and abdominal pain.
Heart -


Low blood pressure, palpitation and fast heart rate.
Gastrointestinal -


Vomiting, indigestion, constipation, flatulence and dry mouth.
Central Nervous System -


Sleeplessness, nervousness, tingling, drowsiness and unsteadiness.
Skin -


Itching and rash.
Miscellaneous -


Difficulty in breathing, gout, back pain, joint pain, increased sweating, decreased sexual activity, ringing in the ear and urinary tract infection.


Other Precautions : 
* Avoid excess dosage.


Storage Conditions : 
Store it at room temperature and protect it from moisture. Keep away from children.

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