Generic Name : Vincristine
Pronunciation : vin-KRIS-teen
Trade Name(s):
India- Alcrist, Biocristin, B-Cristine, Cytocristi, Oncocristin -AQ, Onvinc, Neocristin, Unicristin, Vcr, Vincristin, Vincryst, Vinlon, Vinstin.
International- Oncovin, Vincasar.
Why it is prescribed (Indications) :
This medication is a chemotherapy agent, prescribed for certain types of cancer such as leukemia, Hodgkin disease, and non-Hodgkin lymphomas.
When it is not to be taken (Contraindications):
Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
When it is to be taken :
Adult- PO- The recommended dose is 1.4-1.5 mg/m2 once weekly. Max: 2 mg/week.
How it should be taken :
It comes as a solution for injection to be administered by a healthcare provider into the vein.
Special Instruction :
* Caution should be exercised in patients with history of infection, decrease in blood counts, blood problems due to chemotherapy, liver disease, muscle problems, nerve disease, any allergy, during pregnancy and breastfeeding.
* It may cause dizziness or lightheadedness, do not drive a car or operate machinery while taking this medication.
Side Effects :
Most Common -
Hair loss.
Gastrointestinal -
Constipation, abdominal cramps, weight loss, nausea, vomiting, mouth ulceration, diarrhea, intestinal necrosis and loss of appetite.
Genitourinary -
Painful urination, bed-wetting and increased urination.
Heart -
High/low blood pressure and heart attack.
Blood -
Bone marrow depression.
Miscellaneous -
Fever and headache.
Other Precautions :
* Avoid excess dosage.
Storage Conditions :
Store it in refrigerator (2°-8°C), protect from light.
Pronunciation : vin-KRIS-teen
Trade Name(s):
India- Alcrist, Biocristin, B-Cristine, Cytocristi, Oncocristin -AQ, Onvinc, Neocristin, Unicristin, Vcr, Vincristin, Vincryst, Vinlon, Vinstin.
International- Oncovin, Vincasar.
Why it is prescribed (Indications) :
This medication is a chemotherapy agent, prescribed for certain types of cancer such as leukemia, Hodgkin disease, and non-Hodgkin lymphomas.
When it is not to be taken (Contraindications):
Contraindicated in patients with demyelinating form of Charcot-Marie-Tooth syndrome (an inherited disorder of nerves).
Pregnancy Category : |
|
When it is to be taken :
Adult- PO- The recommended dose is 1.4-1.5 mg/m2 once weekly. Max: 2 mg/week.
How it should be taken :
It comes as a solution for injection to be administered by a healthcare provider into the vein.
Special Instruction :
* Caution should be exercised in patients with history of infection, decrease in blood counts, blood problems due to chemotherapy, liver disease, muscle problems, nerve disease, any allergy, during pregnancy and breastfeeding.
* It may cause dizziness or lightheadedness, do not drive a car or operate machinery while taking this medication.
Side Effects :
Most Common -
Hair loss.
Gastrointestinal -
Constipation, abdominal cramps, weight loss, nausea, vomiting, mouth ulceration, diarrhea, intestinal necrosis and loss of appetite.
Genitourinary -
Painful urination, bed-wetting and increased urination.
Heart -
High/low blood pressure and heart attack.
Blood -
Bone marrow depression.
Miscellaneous -
Fever and headache.
Other Precautions :
* Avoid excess dosage.
Storage Conditions :
Store it in refrigerator (2°-8°C), protect from light.
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