Friday, September 16, 2016

Lansoprazole

Generic Name : Lansoprazole

Pronunciation : lan-SOE-pra-zole

Trade Name(s): 
India- Acilanz Cap, Arlan Cap, Bal-Lanz Cap, Cap Loc Od Cap, Chexid Cap, Culans Cap, Domsin-La Cap, Juniorlanzol Tab, L-30 Cap, Lacy Cap, Lampo Cap, Lan Cap, Lance Cap, Lance-D Cap, Lancer Cap, Lanchek Cap, Lancibay Tab, Lancid Cap, Lancidom Cap, Lancus Enteric-Coated Cap, Lands-30 Cap, Lanip Cap, Lanip-D Cap, Lanoz Tab, Lanpro Cap, Lansec Cap, Lanset Cap, Lanso Cap, Lans-Od Cap, Lansofast Cap, Lansol Cap, Lansomac Cap, Lansoriv Cap, Lansoz Cap, Lanspep Cap, Lanspro Cap, Lanspro-D Cap, Lanzap Cap, Lanzee Cap, Lanzee-Dm Cap, Lanzip-30 Tab, Lanzo Cap, Lanzol Cap, Lanzopen Cap, Lapra-D Cap, Lasole Cap, Lasole-D Cap, Laz-30 Cap, L-Dom Cap, Leed Cap, Leedom Cap, Legend Cap, Lepez Enteric-Coated Cap, Lesozap-D Cap, Levant Cap, Lezo Cap Cap, Liza Cap, Liza-D Cap, Locid-30 Cap, Locid-D Cap, Lp-30 Cap, Lupizole Cap, Okalan Cap, Olez-30 Cap, Prompro Cap, Protogut Cap, Reflan Cap, Sanlap Soft-Gelatin Caps, Splanz Cap, Taurlans-30 Cap, Zapacid Cap, Zes-30 Cap.
International- Prevacid , Prevacid NapraPAC.


Why it is prescribed (Indications) : 
This medication is a proton pump inhibitor, prescribed for gastric ulcer, duodenal ulcer, gastroesophageal reflux disease (GERD), erosive esophagitis (inflammation of esophagus), and Zollinger-Ellison (gastric acid hyper secretion) syndrome. It blocks the enzyme in the stomach that produces acid.





When it is not to be taken (Contraindications): 


Known hypersensitivity.





Pregnancy Category :













A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.


When it is to be taken : 
Adult- PO- The recommended dose is 15 – 30 mg once daily. Higher dose is needed in Zollinger – Ellison syndrome.

How it should be taken : 
It comes as a delayed-release (long-acting) capsule and granules to make a delayed-release solution (liquid) to take by mouth. It is usually taken once a day, before eating. Do not crush or chew the capsules. Swallow the medication whole. Injection administered into the vein.




Special Instruction : 
*While taking sucralfate (Carafate), take it at least 30 minutes after lansoprazole.


*It may affect liver function.


*Gastric malignancy should be ruled out.


* Caution should be exercised in patients with osteoporosis, liver problem, bowel cancer, any allergy, who are taking other medications, during pregnancy and breastfeeding.

Side Effects : 
Central Nervous System-
Headache.

Skin-
Severe allergic reactions.

Eye and ENT-
Speech disorder.

Gastrointestinal-
Diarrhea, abdominal pain, constipation, nausea, inflammation of pancreas and vomiting.

Genitourinary-
Urinary retention.

Blood-
Decrease in white blood cells, platelets, neutrophils, anemia and bleeding.

Liver-
Liver damage.

Miscellaneous-
Injection site pain/reaction and life threatening allergic reactions.

Other Precautions : 
*Do not change the dose or stop taking this medication unless advised by health care provider.


Storage Conditions : 
Injection: Store at 25°C (77°F). Oral: Store at 25°C (77°F). Store it in an airtight container and keep away from children.

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