Tuesday, September 27, 2016

Vancomycin

Generic Name : Vancomycin

Pronunciation : van-koe-MYE-sin

Trade Name(s): 
India- Covancin Vial, Cytovan Inj, Forstaf Vial, Vanacin-Cp Vial, Vancocare Inj, Vancocin Cp Vial, Vancogen Vial, Vancogram-500 Vial, Vancoled Inj, Vancomate Vial, Vancomycin Tab, Vanconex Cp Inj, Vanconis Vial, Vancorid Cp Inj, Vancorin Inj, Vancoser Inj, Vancotar Inj, Vancotech Vial, Vanking Vial, Vanlid Cap, Vanlid Vial, Vanmax Vial, Vansafe Inj, Vantox-Cp Inj, Vconat Inj, Wancosan Vial.
International- Vancomycin Hydrochloride.


Why it is prescribed (Indications) : 
This medication is a glycopeptide antibiotic, prescribed for serious bacterial infections, endocarditis and surgical prophylaxis in major procedures. It kills sensitive bacteria.




When it is not to be taken (Contraindications): 


Hypersensitivity to the drug.





Pregnancy Category :












A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
Adult: IV- The recommended dose is 0.5-2 g/day in 3-4 divided doses for a period of 7-10 days. Dose may be reduced in kidney patients.

How it should be taken : 
It comes as a solution for injection, administered by healthcare provider, with or without food.




Special Instruction : 
*Patient may develop with Ototoxicity (damage to the ear), nephrotoxicity (kidney damage).

*Caution needed for patients with history of kidney impairment, newborns, elderly, during pregnancy and breastfeeding.


*Administer only by slow intra venous injection.


*Change the injection site, to decrease vein inflammation.


*Keep rate of infusion at less than or equal to 10 mg/min rate.


*Monitor kidney and liver functions, serum concentration, blood counts and functioning of the ear regularly.

Side Effects : 
Most Common-
Ear and kidney damage.
Local-

Severe allergic reactions including rash, hives, or itching.
Gastrointestinal-

Inflammation of intestine.
Blood-

Decrease in white blood cell and platelets.
Miscellaneous-

Fever, nausea, dizziness, chills, eosinophilia, low blood pressure, wheezing and difficulty in breathing.

Other Precautions : 
*Discontinue if patient develops tinnitus (ringing in the ear).

Storage Conditions : 
Injection: Store at 15-30°C, far from heat and light.

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