Tuesday, October 18, 2016

Acyclovir

Generic Name : Acyclovir

Pronunciation : (ay sye' kloe ver)

Trade Name(s): 
India- Aciherpin Crm Cream, Aciherpin Tab, Aciv Tab, Acivir Crm Cream, Acivir Dispertab, Acivir Oint Ophth Oint, Acivir Vial, Acv Tab, Acv Vial, Acvirall Dispertab, Alovir Tab, Axovir Inj, Axovir Tab, Cevirin Vial, Civir Dispertab, Clovirax Crm Cream, Clovirax Dispertab, Cutivir Tab, Cyclovir Cream, Cyclovir Oint Eye Oint, Cyclovir Tab, Herperax Oint Cream, Herperax Oint Oint, Herperax Tab, Herpex Crm Cream, Herpex Dispertab, Herpex Tab, Herpil Tab, Herzovir Vial, Kayvir Tab, Koviran Vial, Lovir Tab, Nisivir Vial, Ocuvir Dispertab, Ocuvir Oint Eye Oint, Ocuvir Skin Cream, Okavir Dispertab, Okavir Skin Crm Cream, Ovir Vial, Psyvir 5% Cream, Psyvir Tab, Ridoherp Crm Cream, Ridoherp Tab, Trikase Crm Cream, Trikase Tab, Univir Vial, Vir Inj Vial, Viroderm Oint, Virucid Oint Eye Oint, Vivorax Cream, Zovir Tab, Zovirax Ophthalmic Oint Eye Oint, Zovirax Susp, Zovirax Tab, Zovirax Vial, Zoylex Inj, Zoylex-Dt Dispertab.
International- Zovirax.


Why it is prescribed (Indications) : 
This medication is an antiviral agent, prescribed for herpes simplex, genital herpes, herpes zoster and chickenpox. It slows down the growth and spread of the herpes virus.




When it is not to be taken (Contraindications): 


Hypersensitivity.





Pregnancy Category :













A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.


When it is to be taken : 
Acute Treatment of Herpes Zoster: 800 mg every 4 hours orally, 5 times daily for 7 to 10 days.


Genital Herpes: Treatment of Initial Genital Herpes: 200 mg every 4 hours, 5 times daily for 10 days.


Chronic Suppressive Therapy for Recurrent Disease: 400 mg 2 times daily for up to 12 months, followed by re-evaluation.


Treatment of Chickenpox: Children (2 years of age and older): 20 mg/kg per dose orally 4 times daily (80 mg/kg/day) for 5 days.


Adults and Children over 40 kg: 800 mg 4 times daily for 5 days.

How it should be taken : 
It comes as a tablet, suspension to take by mouth, with or without food. It comes as cream, ointment to apply over the affected area. It also comes as a solution for injection to be administered by a healthcare provider into the vein.





Special Instruction : 

* It may cause sunburn easily, avoid exposure to sunlight or wear proper clothes.

* Caution should be exercised in patients with history of kidney disease, any allergy, during pregnancy and breast-feeding.

* It may lead to dehydration, drink adequate water or liquid.

* It may cause dizziness, drowsiness or lightheadedness, do not drive a car or operate machinery while taking this medication.

* After applying this medication wash your hands thoroughly to prevent passage of infection to others.

* Avoid sexual intercourse or use condom to prevent the spread of virus.

Side Effects : 
General -
Severe allergic reactions, fever, headache, pain and peripheral edema.
Central Nervous System -
Aggressive behavior, agitation, unsteadiness, coma, confusion, decreased consciousness, confusion, dizziness, hallucinations, tingling, epilepsy, drowsiness and tremors.
Gastrointestinal -
Diarrhea, gastrointestinal distress and nausea.
Blood -
Anemia, decrease in white blood cells and platelets.
Liver
Elevated liver function tests, liver inflammation and jaundice.
Musculoskeletal -
Muscle pain.
Skin -
Hair loss, redness, itching, rash and hives.
Eye -
Visual abnormalities.
Genitourinary -
Kidney failure, elevated blood urea nitrogen levels and blood in urine.

Other Precautions : 
* Avoid contact with eyes and excess dosage.


* Avoid alcohol consumption.

Storage Conditions : 
Store it at room temperature (15° to 25°C) and protect from moisture.

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