Generic Name : Raloxifene
Pronunciation : ral-OX-i-feen
Trade Name(s):
India- Bonmax Tab, Bontact Tab, Esserm Tab, Estroact Tab, Evomate Tab, Fiona Tab, Gynista Tab, Osral Tab, Ralista Film-Coated Tab, Ralocium Tab, Ralofen Film-Coated Tab, Ralosto Tab, Ralotab Tab, Ralox Tab, Raloxifene Tembid, Ruftuf Tab, Sermifen, Strong Kit.
International- Evista .
Why it is prescribed (Indications) :
This medication is a selective estrogen receptor modulator (SERM) prescribed for treatment and prevention of osteoporosis in postmenopausal women. It is also used for reduction in risk of invasive breast cancer in postmenopausal women with osteoporosis and those at high risk for invasive breast cancer. It decreases bone turnover and increases bone density.
When it is not to be taken (Contraindications):
Category X : Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
When it is to be taken :
Adult: PO- The recommended dose is 60 mg/day.
How it should be taken :
It comes as a tablet to take by mouth. It is usually taken once a day with or without food.
Special Instruction :
*You should follow the diet and exercise recommended by the doctor regularly.
*Calcium and Vitamin D should be taken if needed.
*Monitor your body weight regularly to prevent bone weakness.
*It may cause blood clots, so avoid sitting in one place.
*It is not recommended for men.
*Caution needed for pregnant women, elderly, and children, patients with history of heart failure, liver or kidney disease, excess in triglycerides in blood.
Side Effects :
Serious adverse effects- Deep vein thrombosis (clotting in the deep veins), pulmonary embolus, stroke.
Most Common-
Hot flushes, leg cramps, sweating, sleep disorders, peripheral edema, vaginal bleeding; flu-like symptoms, rashes, headache.
Gastrointestinal-
Nausea, vomiting, diarrhea, GI disturbances.
Metabolic-
Weight gain.
Musculoskeletal-
Joint pain, muscle pain, inflammation of joints, tendon disorder.
Central Nervous System-
Depression, sleeplessness, dizziness, nerve disease.
Respiratory-
Inflammation of respiratory tract, runny nose, increased cough.
Skin-
Rash, sweating.
Eye-
Inflammation of conjunctiva.
Genitourinary-
Urinary tract infection, inflammation of vagina, vaginal bleeding, uterine disorder.
Potentially Fatal- Endometrial carcinoma and thromboembolic events.
Other Precautions :
*Take exactly as directed by your healthcare provider.
Storage Conditions :
Oral: Store at 15-30°C.Keep this medication in an airtight container, and room temperature. Keep away from children.
Pronunciation : ral-OX-i-feen
Trade Name(s):
India- Bonmax Tab, Bontact Tab, Esserm Tab, Estroact Tab, Evomate Tab, Fiona Tab, Gynista Tab, Osral Tab, Ralista Film-Coated Tab, Ralocium Tab, Ralofen Film-Coated Tab, Ralosto Tab, Ralotab Tab, Ralox Tab, Raloxifene Tembid, Ruftuf Tab, Sermifen, Strong Kit.
International- Evista .
Why it is prescribed (Indications) :
This medication is a selective estrogen receptor modulator (SERM) prescribed for treatment and prevention of osteoporosis in postmenopausal women. It is also used for reduction in risk of invasive breast cancer in postmenopausal women with osteoporosis and those at high risk for invasive breast cancer. It decreases bone turnover and increases bone density.
When it is not to be taken (Contraindications):
Contraindicated in patients with allergy to the drug; active or past history of venous blood clot events including deep vein thrombosis, pulmonary embolism and retinal vein thrombosis, pregnancy, nursing mothers.
Pregnancy Category : |
|
When it is to be taken :
Adult: PO- The recommended dose is 60 mg/day.
How it should be taken :
It comes as a tablet to take by mouth. It is usually taken once a day with or without food.
Special Instruction :
*You should follow the diet and exercise recommended by the doctor regularly.
*Calcium and Vitamin D should be taken if needed.
*Monitor your body weight regularly to prevent bone weakness.
*It may cause blood clots, so avoid sitting in one place.
*It is not recommended for men.
*Caution needed for pregnant women, elderly, and children, patients with history of heart failure, liver or kidney disease, excess in triglycerides in blood.
Side Effects :
Serious adverse effects- Deep vein thrombosis (clotting in the deep veins), pulmonary embolus, stroke.
Most Common-
Hot flushes, leg cramps, sweating, sleep disorders, peripheral edema, vaginal bleeding; flu-like symptoms, rashes, headache.
Gastrointestinal-
Nausea, vomiting, diarrhea, GI disturbances.
Metabolic-
Weight gain.
Musculoskeletal-
Joint pain, muscle pain, inflammation of joints, tendon disorder.
Central Nervous System-
Depression, sleeplessness, dizziness, nerve disease.
Respiratory-
Inflammation of respiratory tract, runny nose, increased cough.
Skin-
Rash, sweating.
Eye-
Inflammation of conjunctiva.
Genitourinary-
Urinary tract infection, inflammation of vagina, vaginal bleeding, uterine disorder.
Potentially Fatal- Endometrial carcinoma and thromboembolic events.
Other Precautions :
*Take exactly as directed by your healthcare provider.
Storage Conditions :
Oral: Store at 15-30°C.Keep this medication in an airtight container, and room temperature. Keep away from children.
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