Thursday, October 6, 2016

Ritodrine

Generic Name : Ritodrine

Trade Name(s): 
India- Miolene Inj, Miolene Tab, Ristore Tab, Ritodine Inj, Ritodine Tab, Ritolan Tab, Ritrod Inj, Ritrod Tab, Tocopar Tab, Uterelax Tab, Utgard Inj, Utgard Tab, Utodin Amp, Utodin Tab, Yutopar Amp, Yutopar Tab.
International- Yutopar.


Why it is prescribed (Indications) : 
This medication is a tocolytic agent, prescribed for uncomplicated premature labour.





When it is not to be taken (Contraindications): 


Contraindicated in patients with high blood pressure during pregnancy, bleeding during pregnancy, intrauterine fetal death, heart disease, miscarriage and cord compression.







Pregnancy Category :













A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.


When it is to be taken : 
Adult: PO- 10 mg 30-60 mins before termination of IV infusion, repeat 2 hourly for 24 hour, then 10-20 mg 4-6 hourly. Max: 120 mg/day.
IV- Initial: Infuse at 0.05 mg/min. Increase gradually till patient responds. Usual: 0.15-0.35 mg/min.
IM 10- mg 3-8 hourly. Maintain for 12-48 hour after contractions have stopped.

How it should be taken : 
It comes as a solution for injection to be administered by a health care provider.




Special Instruction : 
* Caution should be exercised in patients with history of heart disease, concurrent steroids, over active thyroid, heart attack, high blood pressure, sugar, asthma and breastfeeding.



* Monitor plasma glucose and potassium level.



* Monitor maternal pulse count throughout infusion; adjust rate to avoid maternal heartbeat exceeding 140 beats/min.

Side Effects : 
Fast heart rate, palpitation, headache, nervousness, anxiety, nausea and vomiting.



Potentially Fatal- Lung swelling and severe allergic reactions.

Other Precautions : 
* Monitor patient's hydration status to reduce risk of lung swelling. Discontinue treatment if there are signs of lung swelling.

Storage Conditions : 
Normally handled and stored by health care providers.

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