Monday, October 24, 2016

Alfacalcidol

Generic Name : Alfacalcidol

Pronunciation :  al-fă-kal′si-dol

Trade Name(s): 
India- Acal, Albonate, Alcal, Alcalci, Alcals Plu, Alcidol, Alciriz, Alfa caps, Alfa Surec, Alfabol, Alfacal, Alfacal Pl, Alfacare, Alfacip, Alfacip Pl, Alfa-D3, Alfa-Maxic, Alfa Osteb, Alfarich, Alfaest, Alfasureca, Alfatec C, Alfazic, Alfex, Alfex-Bt, Allnet, Alpha B Ca, Alphabond, Alphacad, Alphadol, Alphadol-C, Alpidol, Bonical-A, Bonlee, Cad Alpha, Cal Ci San, Calcad – Bc, Calceedol, Calcif, Calcijiex, Calcit Sg, Calfa Plus, Calfa-D, Calrage, Calsure Op, calvon A, Canadol, Caphidol C, Cascal, Cason D, Cecal Plus, Cidocal, Densica Al, Dolvic, Elcadol, Flabone, Glycal A, Gr-Alfa, Ascal, Ifycal-Ad, Intradol, Ipridol, Kalcid, Kaliber, Kalory, Kalpha, Milkal, Minroset, Minoroset-C, Ob-Cal A, One Alpha, Orocal, Ospical Op, Ossopan Al, Pharmacal, Qtr-Alfa, Refirm, Rical-Alfa, Rulcal, Salcidol, Sayocal A, Shelcal-Os, Shel-D-Os, Simcal Bc, Skelbon, Spercal-Al, Supracal-A, Swidol-A, Unical-Bc, Vitalpha, Vitlpha C, Zaxial, Zaxial Plu, Zovical A.
International- Alfa-D, One-Alpha.


Why it is prescribed (Indications) : 
This medication is an analogue of vitamin D, prescribed for hypocalcaemia, hypoparathyroidism, hypophosphataemia, renal osteodystrophy, and osteomalacia.




When it is not to be taken (Contraindications): 


Contraindicated in patients with high blood calcium, phosphate, and magnesium and known hypersensitivity.





Pregnancy Category :












A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
Adult- PO- The recommended starting dose is 1mcg/day. Maintenance: 0.25-1 mcg/day.


Adult- IV- The recommended initial dose is 1 mcg per dialysis two to three times a week.

How it should be taken : 
It comes as a capsule to take by mouth, with food.


It also comes as a solution for injection to be administered by a healthcare provider into the vein.




Special Instruction : 
* Caution should be exercised in patients with history of kidney stones, heart or kidney disease, high level of calcium in blood, any allergy, who are taking other medications, during pregnancy and breastfeeding.


* Monitor blood electrolytes level regularly while taking this medication.



* Monitor serum levels of calcium in patients with kidney failure.


Side Effects : 
Gastrointestinal -


Loss of appetite, nausea, vomiting, diarrhea and increased thirst.
Central Nervous System -


Headache, fainting and lack of energy.
Skin -


Increased sweating, itching, rash and hives.
Genitourinary: -

Increased urination, kidney impairment, and excessive urinary calcium excretion.

Other Precautions : 
* Avoid excess dosage.


Storage Conditions : 
Capsules: Store it at room temperature (25°C), and in an airtight container.



Injection: Store it in a cool place (below 15°C).


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