Generic Name : Venlafaxine
Pronunciation : ven' la fax een
Trade Name(s):
India- Dalium Tab, Envelaf Xr-Cap, Faxiven-Xr Tab, Flavix Tab, Flavix Xr-Tab, Sentosa Er-Tab, Sentosa Tab, Venaxin-Sr -Tab, Venaxin-Sr Tab, Vendep Xr Er-Cap, Venfax-Pr Er-Cap, Veniz-Xr Er-Cap, Venjoy-Xr Extentab, Venla Cap, Venla Suscap, Venlift Od Cap, Venlift Od Tab, Venlift Tab, Venlor Tab , Venlor-Xr Cap, Ven-Od Cap, Venrea Ercap, Vexor Extentab.
Internationl-Effexor.
Why it is prescribed (Indications) :
This medication is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI), prescribed for depression, generalized anxiety disorder, social anxiety disorder, and panic disorder.
When it is not to be taken (Contraindications):
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
When it is to be taken :
For depression- Initial: 75 mg/day in 2-3 divided doses, increase slowly if needed. Max: 375 mg/day.
For anxiety Extended release- Initial: 75 mg once daily, may increase slowly if needed. Max: 225 mg/day.
For panic disorder- 37.5 mg once daily for 1st 7 days, may increase slowly if needed. Max: 225 mg/day.
How it should be taken :
It comes as a tablet or extended-release capsule to take by mouth. Take tablet 2times/day and extended-release capsule once daily in the morning or evening with food.
Special Instruction :
*It may cause moderate to severe liver or kidney problems. Conditions which may be worsened by increase in heart rate.
* Caution should be exercised in patients with history of heart attack, bleeding disorder, epilepsy, hypomania or mania, elderly, during pregnancy.
* Monitor blood pressure, serum cholesterol regularly.
* Monitor closely during early therapy until depression improves due to increased risk of suicide.
* Discontinue if seizure develops or increase in seizure frequency.
Side Effects :
Heart-
Widening of blood vessels,high blood pressure, palpitations, fast heart beat, low blood pressure, deep vein blood clot, ECG abnormalities (eg, QT prolongation), irregular heart beat.
Central Nervous System-
Headache, drowsiness, dizziness, sleeplessness, nervousness, weakness, anxiety, tremor, abnormal dreams, agitation, depression, increased muscle tightness, tingling, twitching, abnormal thinking, confusion, loss of memory, impaired coordination and balance, involuntary movements, shock-like electrical sensations.
Skin-
Sweating, rash, itching, redness of the skin, toxic epidermal blistering.
Eye and ENT-
Throat inflammation, abnormal vision, dilation of pupil, taste perversion, sudden eye pressure, eye bleeding.
Gastrointestinal-
Nausea, dry mouth, loss of appetite, constipation, abdominal pain, diarrhea, vomiting, indigestion, flatulence, eructation, increased appetite,bleeding.
Genitourinary-
Abnormal ejaculation, impotence, decreased sexual activity, impaired urination, orgasm disturbance, urinary frequency, albumin in urine, painful menstruation, weak urination, vaginal inflammation, urinary retention.
Blood-Discoloration of skin, decrease in white blood cell, decrease in platelets, and neutrophils.
Liver-
Liver function abnormalities, liver damage, necrosis, or failure, and fatty liver.
Metabolic-
Weight loss, edema, weight gain
Respiratory-
Inflammation of bronchus, cough increased, difficulty in breathing, interstitial lung disease.
Miscellaneous-
Yawning, chills, flu-like syndrome, infection, accidental injury, chest pain, trauma, joint pain, fever, neck pain, chest pain, birth defect, bleeding, increased prolactin, night sweats, high concentration of eosinophils, kidney failure.
Other Precautions :
*Avoid abrupt withdrawal. Withdraw gradually over at least 1 to 2 week.
Storage Conditions :
Oral: Store below 30°C. Store it in an airtight container and keep away from children.
Pronunciation : ven' la fax een
Trade Name(s):
India- Dalium Tab, Envelaf Xr-Cap, Faxiven-Xr Tab, Flavix Tab, Flavix Xr-Tab, Sentosa Er-Tab, Sentosa Tab, Venaxin-Sr -Tab, Venaxin-Sr Tab, Vendep Xr Er-Cap, Venfax-Pr Er-Cap, Veniz-Xr Er-Cap, Venjoy-Xr Extentab, Venla Cap, Venla Suscap, Venlift Od Cap, Venlift Od Tab, Venlift Tab, Venlor Tab , Venlor-Xr Cap, Ven-Od Cap, Venrea Ercap, Vexor Extentab.
Internationl-Effexor.
Why it is prescribed (Indications) :
This medication is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI), prescribed for depression, generalized anxiety disorder, social anxiety disorder, and panic disorder.
When it is not to be taken (Contraindications):
Contraindicated in patients who are taking MAOIs or who have taken MAOIs within 14 days, and hypersensitivity.
Pregnancy Category : |
|
When it is to be taken :
For depression- Initial: 75 mg/day in 2-3 divided doses, increase slowly if needed. Max: 375 mg/day.
For anxiety Extended release- Initial: 75 mg once daily, may increase slowly if needed. Max: 225 mg/day.
For panic disorder- 37.5 mg once daily for 1st 7 days, may increase slowly if needed. Max: 225 mg/day.
How it should be taken :
It comes as a tablet or extended-release capsule to take by mouth. Take tablet 2times/day and extended-release capsule once daily in the morning or evening with food.
Special Instruction :
*It may cause moderate to severe liver or kidney problems. Conditions which may be worsened by increase in heart rate.
* Caution should be exercised in patients with history of heart attack, bleeding disorder, epilepsy, hypomania or mania, elderly, during pregnancy.
* Monitor blood pressure, serum cholesterol regularly.
* Monitor closely during early therapy until depression improves due to increased risk of suicide.
* Discontinue if seizure develops or increase in seizure frequency.
Side Effects :
Heart-
Widening of blood vessels,high blood pressure, palpitations, fast heart beat, low blood pressure, deep vein blood clot, ECG abnormalities (eg, QT prolongation), irregular heart beat.
Central Nervous System-
Headache, drowsiness, dizziness, sleeplessness, nervousness, weakness, anxiety, tremor, abnormal dreams, agitation, depression, increased muscle tightness, tingling, twitching, abnormal thinking, confusion, loss of memory, impaired coordination and balance, involuntary movements, shock-like electrical sensations.
Skin-
Sweating, rash, itching, redness of the skin, toxic epidermal blistering.
Eye and ENT-
Throat inflammation, abnormal vision, dilation of pupil, taste perversion, sudden eye pressure, eye bleeding.
Gastrointestinal-
Nausea, dry mouth, loss of appetite, constipation, abdominal pain, diarrhea, vomiting, indigestion, flatulence, eructation, increased appetite,bleeding.
Genitourinary-
Abnormal ejaculation, impotence, decreased sexual activity, impaired urination, orgasm disturbance, urinary frequency, albumin in urine, painful menstruation, weak urination, vaginal inflammation, urinary retention.
Blood-Discoloration of skin, decrease in white blood cell, decrease in platelets, and neutrophils.
Liver-
Liver function abnormalities, liver damage, necrosis, or failure, and fatty liver.
Metabolic-
Weight loss, edema, weight gain
Respiratory-
Inflammation of bronchus, cough increased, difficulty in breathing, interstitial lung disease.
Miscellaneous-
Yawning, chills, flu-like syndrome, infection, accidental injury, chest pain, trauma, joint pain, fever, neck pain, chest pain, birth defect, bleeding, increased prolactin, night sweats, high concentration of eosinophils, kidney failure.
Other Precautions :
*Avoid abrupt withdrawal. Withdraw gradually over at least 1 to 2 week.
Storage Conditions :
Oral: Store below 30°C. Store it in an airtight container and keep away from children.
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