Friday, October 21, 2016

Esmolol

Generic Name : Esmolol

Pronunciation : ESS-mow-lall

Trade Name(s): 
India- Cardesmo Vial, Esmocard Inj, Esocard Vial, Miniblock Inj, Neotach Vial.
International- Brevibloc.


Why it is prescribed (Indications) : 
This medication is an antiarrhythmic agent, prescribed for high blood pressure and to control heart rate.




When it is not to be taken (Contraindications): 


Contraindicated in patients with slow heart rate, heart block greater than first degree, poor blood supply or over heart failure.







Pregnancy Category :












A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
Adult: IV- Arrhythmias- As HCl: Loading dose: 500 mcg/kg; Maintenance: 50 mcg/kg/min for 4 minutes. If response is unsatisfactory within the 1st 5 minutes, give 2nd loading dose of 500 mcg/kg, then maintenance infusion at 100 mcg/kg/min for 4 minutes.

Perioperative HTN and/or tachycardia during anesthesia: Loading dose: 80 mg, then 150 mcg/kg/min via infusion, up to 300 mcg/kg/min if needed. After anesthesia: Infuse 500 mcg/kg/min for 4 minutes, and then infuse at 300 mcg/kg/min if needed. Postoperative: Loading dose: 500 mcg/kg, maintenance: 50 mcg/kg/min for 4 minutes.


How it should be taken : 
It comes as a solution for injection, to be administered by a healthcare provider into the vein.




Special Instruction : 
* Caution should be exercised in patients with history of low blood pressure, diabetes, heart, respiratory diseases, kidney impairment, children, during pregnancy and breastfeeding.


* Avoid alcohol consumption while taking this medication.


* It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.

Side Effects : 
Heart-

Low blood pressure, chest pain, fainting, low heart rate and flushing.
Central Nervous System-

Dizziness, drowsiness, confusion, headache, agitation, fatigue, anxiety, lightheadedness, weakness and tingling.
Respiratory-

Asthma, wheezing, difficulty in breathing, nasal congestion and abnormal breathing sounds.
Gastrointestinal-
Nausea, vomiting, indigestion, constipation, dry mouth and abdominal discomfort.
Miscellaneous-

Urinary retention, speech disorder, abnormal vision, rigors and fever.

Other Precautions : 
*Take full course of treatment.

Storage Conditions : 
Store it at room temperature (25°C), and in an airtight container. Keep away from children.

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