Thursday, October 6, 2016

Epoetin beta-methoxy polyethylene glycol

Generic Name : Epoetin beta-methoxy polyethylene glycol

Pronunciation : e POE e tin BAY ta meth OX ee pol ee ETH il een GLYE kol

Trade Name(s): 
India- Mircera Pf-Syringe, Neorecormon Pf-Syringe, Recormon Pf-Syringe.
International- Epogen, Eprex, Procrit.


Why it is prescribed (Indications) : 
This medication is an erythropoiesis-stimulating agent, prescribed for anemia in people with chronic kidney failure.





When it is not to be taken (Contraindications): 


Contraindicated in patients with uncontrolled hypertension and hypersensitivity.





Pregnancy Category :












A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
Adult- IV- Initial dose: The recommended dose is 0.6 mcg/kg.

How it should be taken : 
It comes as a solution for injection to be administered by a healthcare provider into the vein.




Special Instruction : 
* Caution should be exercised in patients with history of heart disease, high blood pressure, cancer, seizures, blood cell disorder, blood clotting disorder, or a history of stroke, blood clots, or heart attack, high blood pressure, elderly, during pregnancy and breastfeeding.

* Patient may develop with increased risk of kidney failure, heart attack, heart failure and stroke; if it is so stop this medication immediately.


* Monitor blood pressure, hemoglobin level, signs and symptoms of allergic reactions regularly while taking this medication.

Side Effects : 
Severe Effect -
Tumor growth, heart failure, kidney damage, high blood pressure, seizures and blood clot events.
Heart -

Low blood pressure.
Gastrointestinal -

Diarrhea, vomiting and constipation.
Infections -

Upper respiratory tract infection and urinary tract infection.
Central Nervous System -

Headache.
Musculoskeletal -

Muscle spasms, back pain and pain in extremities.
Metabolic -

Excess fluid.
Respiratory -

Increased cough.

Other Precautions : 
* Avoid excess dosage.

Storage Conditions : 
Store it in refrigerator (2° to 8°C), do not freeze it.


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